Detalhe da pesquisa
1.
Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis.
Nature
; 616(7958): 755-763, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37046083
2.
Genetic diversity fuels gene discovery for tobacco and alcohol use.
Nature
; 612(7941): 720-724, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36477530
3.
Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program.
Nature
; 590(7845): 290-299, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33568819
4.
Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed whole-genome sequencing study.
Am J Hum Genet
; 110(10): 1704-1717, 2023 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37802043
5.
Identification of type 2 diabetes loci in 433,540 East Asian individuals.
Nature
; 582(7811): 240-245, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32499647
6.
Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes.
Am J Hum Genet
; 109(1): 81-96, 2022 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34932938
7.
A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies.
Nat Methods
; 19(12): 1599-1611, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36303018
8.
Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry.
Am J Hum Genet
; 108(4): 564-582, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33713608
9.
Allele-specific variation at APOE increases nonalcoholic fatty liver disease and obesity but decreases risk of Alzheimer's disease and myocardial infarction.
Hum Mol Genet
; 30(15): 1443-1456, 2021 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33856023
10.
Metabolomic profiling of glucose homeostasis in African Americans: the Insulin Resistance Atherosclerosis Family Study (IRAS-FS).
Metabolomics
; 19(4): 35, 2023 04 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37005925
11.
Methods for estimating insulin resistance from untargeted metabolomics data.
Metabolomics
; 19(8): 72, 2023 08 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37558891
12.
Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits.
Am J Hum Genet
; 104(1): 112-138, 2019 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30595373
13.
Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations.
PLoS Genet
; 15(12): e1008500, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31869403
14.
Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans.
Hum Genomics
; 13(1): 21, 2019 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31092297
15.
Symptoms Suggestive of Gastroparesis in a Community-Based Cohort of European Americans and African Americans with Type 2 Diabetes Mellitus.
Dig Dis Sci
; 65(8): 2321-2330, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31820181
16.
QRS duration is associated with all-cause mortality in type 2 diabetes: The diabetes heart study.
J Electrocardiol
; 58: 150-154, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-31895990
17.
Plasma apoM and S1P levels are inversely associated with mortality in African Americans with type 2 diabetes mellitus.
J Lipid Res
; 60(8): 1425-1431, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31133557
18.
Genome-wide interaction with the insulin secretion locus MTNR1B reveals CMIP as a novel type 2 diabetes susceptibility gene in African Americans.
Genet Epidemiol
; 42(6): 559-570, 2018 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-29691896
19.
Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin.
Am J Hum Genet
; 99(1): 56-75, 2016 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27321945
20.
The African Descent and Glaucoma Evaluation Study (ADAGES) III: Contribution of Genotype to Glaucoma Phenotype in African Americans: Study Design and Baseline Data.
Ophthalmology
; 126(1): 156-170, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29361356